Realizing the value of DotLocal(.local) dll redirection in private testing, a change is made in Windows Vista, that when the registry [I]HKLM\Software\Microsoft\WindowsNT\CurrentVersion\Image File Execution Options!DevOverrideEnable:REG_DWORD[/I] is set to 1, DotLocal(.local) dll redirection will be enabled, even if the application has a manifest.
This change is in Windows Vista Beta1 and beyond. It will require a machine reboot to make the change take effect.